diff --git a/UPGRADE.rst b/UPGRADE.rst
index b214a15526..47a8cb9c88 100644
--- a/UPGRADE.rst
+++ b/UPGRADE.rst
@@ -18,7 +18,7 @@ instructions that may be required are listed later in this document.
 
    .. code:: bash
 
-       pip install --upgrade --process-dependency-links matrix-synapse
+       pip install --upgrade matrix-synapse
 
        # restart synapse
        synctl restart
diff --git a/changelog.d/4485.misc b/changelog.d/4485.misc
new file mode 100644
index 0000000000..8aa0aeab2a
--- /dev/null
+++ b/changelog.d/4485.misc
@@ -0,0 +1 @@
+Remove deprecated --process-dependency-links option from UPGRADE.rst